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Table 1 XELODA Dose Calculation According to Body Surface Area Dose Level 1250 mg/m2 Twice a Day Number of Tablets to be Taken at Each Dose (Morning and Evening) Surface Area (m2) Total Daily Dose* (mg) 150 mg 500 mg In combination with docetaxel, the recommended dose of XELODA is 1250 mg/m2 twice daily for 2 weeks followed by a 1-week rest period, combined with docetaxel at 75 mg/m2 as a 1-hour intravenous infusion every 3 weeks. Pre-medication, according to the docetaxel labeling, should be started prior to docetaxel administration for patients receiving the XELODA plus docetaxel combination. Table 1 displays the total daily dose of XELODA by body surface area and the number of tablets to be taken at each dose.
Who Makes Xeloda? It is made by Hoffmann-La Roche, Inc. What Is It Used For? Specific uses of the drug include the treatment of: Colon cancer after surgery. Colon or rectal cancer that has spread to other parts of the body (metastatic colorectal cancer). Breast cancer that has spread to other parts of the body (metastatic breast cancer) -- this is treated with a combination of Xeloda and docetaxel (Taxotere®). Metastatic breast cancer in people who have not improved after treatment with other medicines, including paclitaxel (Onxol®, Taxol®) and anthracycline chemotherapy medications, or for those who cannot take any more anthracycline medications.
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